After their transfer from the Evo-Stik Northern League South, AFC Rushden and Diamonds begin with a home fixture against Hanwell Town.
The phoenix club missed out on promotion last season losing in the play-off semi-finals against eventual winners Witton Albion, while Hanwell secured themselves a top-half finish.
Thame United, winners of the Hellenic Premier Division, visit Chalfont St Peter with Combined Counties champions Hartley Wintney – finally allowed promotion following improvements to their ground – hosting Northwood.
Moneyfields were the third team to gain promotion, winning the Wessex League, and they host Kempston Rovers, who missed out on the play-offs by a point.
Meanwhile, relegated Cambridge City and Hayes and Yeading both start with home games against Ashford Town and Aylesbury.
Last season’s play-off losers Egham Town and Barton Rovers play each other in a testing first fixture while finalists Marlow travel to Arles Town.
AFC Dunstable finished two points off fifth place last season and they’ll be payed a visit by Fleet Town on the opening day.
Elsewhere, Aylesbury United take on Beaconsfield Town and Uxbridge host Bedford Town.